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PUBLICATIONS

Journal Articles

  • Banse X, Devogelaer JP, Munting E, Delloye C, Cornu O, Grynpas MD. (2001) Inhomogeneity of vertebral cancellous bone. Bone 28(5): 563 - 571  (May)
  • Hunter GK, Poitras MS, Underhill M, Grynpas MD, Goldberg HA. (2001) Induction of collagen mineralization by a bone sialoprotein-decorin chimeric protein. J Biomed Materials Res (in press)
  • Pilliar RM, Filiaggi M, Wells JD, Grynpas MD, Kandel RA. (2001) Porous calcium polypyhosphate scaffolds of bone substitute applications—in vitro characterization. J Biomaterials (in press)
  • Porter NL, Pilliar RM, Grynpas MD. (2001) Solid freeform fabrication of porous calcium polyphosphate: processing parameter and in vitro degradation characteristics. (in press)

  • Boutros CP, Trout DR, Kasra M, Grynpas MD. (2000) The effect of repeated freeze-thaw cycles on the biomechanical properties of canine cortical bone. Vet Comp Orthop Traumatol 13:59-64  (Jul)
  • Grynpas MD, Chachra D, Lundon K. (2000) Bone quality in animal models of osteoporosis. Drug Development Research 49:146-158  (Jul)





  • Cheng P-T, Bader SM, Grynpas MD. (1995) Biphasic effects of Fluoriole on canine cortical and cancellous bone. Cells and Materials 5(3): 271-282.
  • Mahaney WC, Stambolic A, Knezevich M, Hancock RGV, Aufreiter S, Sanmugadas K, Kessler MJ, and Grynpas MD. (1995) Geophagy amongst Rhesus macaques on Cayo Santiago, Puerto Rico. Primates 36(3): 323-333.

  • Grynpas MD, Gahunia HK, Yuan J, Pritzker KPH, Hartman D, Tupy J. (1994) Analysis of collagens solubilized from cartilage of normal and spontaneously osteoarthritic Rhesus monkey. Osteoarthritis and Cartilage 2: 227-234
  • Grynpas MD, Holmyard D, Pritzker KP. (1994) Bone mineralization and histomorphometry in biopsies of patients treated with fluoride. Cells and Materials 4(3): 287-297
  • Torontali M, Koo I, Holmyard D, Grynpas MD, and Tenenbaum HC. (1994) Assessment of mineral density in bone formed in vitro. Cells and Materials 4(2): 125-134.

  • Lucas S, Bogoch E, Nespeca R, Grynpas MD. (1993) Bone changes induced in a rabbit model of experimental arthritis. Eur J Exp Muskuloskel Res 1: 121-129


  • Grynpas MD, Pritzker KPH, Very JM, Mertz B. (1991) Changes in mineralization profiles due to long term administration of APD in the dog. In: "Osteoporosis 90" ed. by C. Christiansen, Osteopress, Copenhagen, pp. 1358-1360.
  • Tenenbaum HC, Richards J, Holmyard D, Mamujee H, Grynpas MD. (1991) The effect of fluoride on osteogenesis in vitro. Cells and Materials 1(4): 317-327

  • Grynpas MD, Châteauvert JMD, Pritzker KPH. (1990) Determining the elemental composition of articular cartilage: A comparison between human and non-human primates. In: Methods of research in cartilage, A. Maroudas and K. Kuettner ed. Acad. Press, N.Y., pp. 248-251
  • Pritzker KPH, Châteauvert J, Grynpas MD, Kessler MJ. (1990) Studies of naturally occurring degenerative arthritis in Rhesus macaques as a model for degenerative arthritis in man. In: Methods of research in cartilage, A. Maroudas and K. Kuettner ed. Acad. Press, N.Y., pp. 341-342

  • Grynpas MD. (1989) Bone quality and quantity. Future Health 11(1): 7-8.
  • Hancock RGV, Grynpas MD, Pritzker KPH. (1989) The abuse of bone analyses for archeological dietary studies. Archeometry 31:  169-179.

  • Cheng P-T, Grynpas MD. (1988) Mineralization in fluoridated cortical bone. In: "Osteoporosis" ed. by C. Christiansen, J.S. Johansen, B.J. Riis, Osteopress, Copenhagen, Vol. 2 p. 876-878.
  • Grynpas MD, Katz I, Pritzker KPH. (1988) Bone quality and bone quantity in osteoporosis. In "Osteoporosis 87" ed. by C. Christiansen, J.S. Johansen, B.J. Riis, Osteopress, Copenhagen, Vol. 1 p.364-366.

  • Grynpas MD. (1987) Calcified tissue changes in microgravity (an overview). In: Proceedings "Spacebound 87". National Research Council of Canada, Ottawa, p.129-130.
  • Grynpas MD, Pritzker KPH, Hancock RGV. (1987) Neutron activation analysis of bulk and selected trace elements in bones using a low flux slowpoke reactor. Biological Trace Elements Research 13: 333-344.
  • Hancock RGV, Grynpas MD, Alpert B. (1987) Are archeological bones similar to modern bones?  An INAA assessment. J Radioanalyt Nucl Chem 110(1): 283-91.

  • Grynpas MD, Pritzker KPH, Simmons ED, Hancock RGV, Harrison JE. (1986) Is fluoridated bone different from non-fluoridated bone? Cell mediated calcification and matrix vesicles. Ed. by Y. Ali, Elsevier Science, p 409-414.

  • Bonar LC, Grynpas MD, Roberts JE, Griffin RG, Glimcher MJ. (1985) Physical and chemical characterization of the development and maturation of bone mineral. In:  The Chemistry and Biology of Mineralized Tissues, ed. by W.T. Butler pp.  226-233.
  • Pritzker KPH, Cheng P-T, Hunter GK, Grynpas MD, Kessler M, Renlund RC. (1985) In vitro and in vivo models of calcium pyrophosphate crystal formation. In:  The Chemistry and Biology of Mineralized Tissues, ed. by W.T. Butler, pp.  381-384.

  • Grynpas MD, Bonar LC, Glimcher MJ. (1984) X-ray diffraction radial distribution function studies on bone mineral and synthetic calcium phosphate. J Material Sci 19: 723-737


  • Glimcher MJ, Bonar LC, Grynpas MD, Landis WJ and Roufosse AH. (1982) Recent studies of bone mineral:  is the amorphous calcium phosphate theory valid? J Crystal Growth 53: 100-119
  • Grynpas MD, Etz ES, Landis WJ. (1982) Studies of calcified tissue by raman microprobe analysis. In:  Microbeam Analysis 1982, San Francisco, San Francisco Press.
  • Landis WJ, Grynpas MD, Latanisian RM, Martin JR. (1982) Mineralized biological tissues studied by auger electron and x-ray photoelectron spectroscopy. In:  Microbeam Analysis 1982, San Francisco, San Francisco Press.
  • Sisterson JM, Schneider RJ, Tibbets PH, Grynpas MD, Bonar LC. (1982) The reaction31p(p, 3p)29 al and its use in measuring Ca/P molar ratio in chemical compounds. J Radioanalytical Chemistry 71: 509-518.

  • Eyre DR, Grynpas MD, Shapiro FD and Creasmen CM. (1981) Mature crosslink formation & molecular packing in articular cartilage collagen. Seminars in Arthritis and Rheumatism II (Supp1): 46-47
  • Grynpas MD, Bonar LC, Glimcher MJ. (1981) On the subject of amorphous calcium phosphate. The Chemistry and Biology of Mineralized Connective Tissues. ed. by A. Veis, Elsevier North-Holland, New York p. 279-283.

  • Grynpas MD, Bonar LC. (1980) EXAFS studies of the mineralized phase of bone and other mineralized tissues. SSRL Report (302), May.

  • Grynpas M, Lindley PF. (1979) Crystal and molecular structures of the 3 -acetoxy & 3 -benzoxy derivatives of a-amyrin. J Crystal Mol Structure 9(4): 199-217
  • Grynpas MD, Bonfield W, Young RJ. (1979) Slowly propagating fractures in bone. Proceedings of the 7th New England Bioengineering Conference, Troy, New York, March 1979, pp. 94-98.

  • Spencer M, Grynpas M. (1978) Hydroxyapatite for chromatography.  1.  Physical and chemical properties of different preparations. J Chromatography 166: 423-434

  • Grynpas M, Bowman J, Bonfield W. (1977) HDPE-hydroxyapatite, a biocompatible still plastic composite for protheses. Report to the Science Research Council, London, December 1977.

  • Grynpas M. (1976) The crystallinity of bone material. Journal of Materials Science II: 1691-1696
  • Grynpas M. (1975) Studies on the structure of human bone and crystallographic structure determination of organic molecules.  Ph.D. Thesis, London University
  • Grynpas M, Lindley P.F. (1975) The crystal and molecular structure of 1-piperoylpipidine. Acta Crystallographica 31B: 2663-2667
  • Grynpas M. (1970) Etudes Des Transitions De Phases Dans Un Modele Reticulaire.  Memoire De License. Bruxelles University

 

Papers in Refereed Conference Proceedings

  • Grynpas MD, Kasra M, Acito A. (1996) The mechanical properties of canine bone after pamidronate treatment. In: Bisphosphonates - Improved Treatment of Osteolysis in Malignant and Non-malignant Indications. eds. K. Possinger and R. Ziegler, Ciba-Geigy Verlag, Wehr, pp.93-106.

  • Kasra M, Parnianpour M, Wang JL, Shirazi-Adi A, and Grynpas MD. (1998) Mechanical behaviour of annulus fibrosus under tensile dynamic loading: effect of loading rate. In: Integrated Design and Process Technology. eds. A.E. Egin and A. Ertas Society for Design and Process Science, USA, Vol. 1, pp. 49-54.

  • Filiaggi MJ, Wells JD, Peel SAF, Pilliar RM, Grynpas MD, Kandel RA. (1998) Condensed calcium phosphate for soft tissue and bone repair/regeneration. In: Bioceramics Volume 11, (eds) LeGeros RZ, LeGeros JP. World Scientific Publishing Co. Pte. Ltd., New York, (Nov) pp. 341-344

 

Abstracts  (* = supervised students)

  • Lee L, Lee J, Casper R, Grynpas MD. (2001) Skeletal effects Of Bap/DMBA and Resveratrol In estrogen-repleted OVX rats. European Calcium Tissue Conference, June 5-10, Madrid, Spain.
  • Waldman SD, Sun YL, Grynpas MD, Pilliar RM, Kandel RA. (2001) The effect of chondrocyte subpopulations on the composition and load-bearing capacity of tissue-engineered cartilage. Biomaterials Society meeting, April 24-29, 2001, St Paul, Minnesota.

  • Agarwal SC, Dumitriu M, Grynpas MD. (2000) Differences between medieval and modern trabecular bone architecture. Amer Assoc Physical Anthropologists Conference, San Antonio TX, April
  • Agarwal S, Dumitriu M, Grynpas MD. (2000) A comparison of bone quality in past and modern populations. World Congress in Osteoporosis 2000, Chicago, IL, June 15-18
  • Agarwal SC, Dumitriu M, Grynaps MD. (2000) Sex differences in trabecular architecture in past populations. Annual meeting of the ASBMR, September 22-26, Toronto, Canada
  • Bhardwaj T, Pilliar RT, Grynpas MD, Filiaggi M, Kandel R. (2000) An in vitro study of the effect of pore size on tissue engineered cartilagenous tissue formed on porous titatnium alloy substrates. World Biomaterials Conference, Hawaii, May
  • Cerroni AM, Grynpas MD. (2000) Vertebral osteophytosis/Degenerative disc disease (VO/DDD) in the rhesus monkeys of Cayo Santiago. Amer Assoc Physical Anthropologists Conference, San Antonio TX, April
  • Chachra D, Limeback H, Gross AE, Hutchinson CH, Zukor D, Schwartz M, Grynpas MD. (2000) Does accumulated fluoride alter the mechanisms and architecture of human bone? IADR Meeting, Washington DC, March
  • Chachra D, Lee JM, Kasra M, Grynpas MD. (2000) Differential effects of ovariectomy on the mechanical properties of cortical and cancellous bone from aged rats. Rocky Mountain Bioengineering Symposium, Colorado Spring, CO, April 14-16
  • Chachra D, Limeback H, Gross AE, Hutchinson CH, Zukor D, Schwartz M, Grynpas MD (2000) Does life-long ingestion of fluoridated water alter bone quality in humans? World Congress in Osteoporosis 2000, Chicago, IL, June 15-18
  • Chachra D, Limeback H, Gross AE, Hutchinson CH, Zukor D, Schwartz M, Grynpas MD. (2000) Life-long ingestion of fluoride and its effect on bone quality. Annual meeting of the ASBMR, September 22-26, Toronto, Canada
  • Ekstein S, Moran E, Kasra M, Grynpas MD, James D, Bogoch E. (2000) The effect of arthritis on the mechanical properties of the cortex in long bones. 46th Annual Meeting, Orthopaedic Research Society, Orlando, Fla, March 12-15
  • Elsubeihi ES, Grynpas MD, Zarb GA, Heersche JNM. (2000) The effect of ovariectomy on bone mineral density of edentulous and dentate mandible. Annual meeting of the ASBMR, September 22-26, Toronto, Canada
  • Grynpas MD, Kasra M, Kandel RA. (2000) The effect of zoledronate on bone quality in a canine model of aseptic loosening of hip implant. 5th Workshop on Bisphosphonates, Davos, Switzerland, April 5-7
  • Grynpas MD, Kasra M, Kandel RA, White L, Binnington A. (2000) Bone changes due to bisphosphoanate treatment in a model of aseptic loosening. World Congress in Osteoporosis 2000, Chicago, IL, June 15-18
  • Kasra M, Farrington J, Grynpas MD. (2000) Viscoelastic behaviour of trabecular bone from osteorthritic femoral head. World Biomaterials Conference, Hawaii, May 15-20
  • Kasra M, Grynpas MD, Soric R, Arnaud S. (2000) A clinical evaluation of vibration testing in the assessment of osteoporosis. ASME, November
  • Pilliar RM, Filiaggi MJ, Grynpas MD, Kandel RA, Hong J. (2000) Promising prospects for, and perplexing problems in processing of porous polyphosphate products – Novel tissue-engineered prostheses. 12th Canadian Materials Science Conferences, Kingston, ON Canada, June 6-9
  • Robertson KA, Luzzi K, Grynpas MD, Goldberg HA, Hunter GK (2000) Effects of albumin and osteoponting on hydroxyapatite growth habit. Annual meeting of the ASBMR, September 22-26, Toronto, Canada.
  • Simmons ED, Kuhele J, Lee J, Lee L, Grynpas MD. (2000) Evaluation of metabolic bone disease as a risk factor for lumbar fusion. International Society for the Study of Lumbar Spine, June 19-23, Edinborough, Scotland
  • Woodfield T, Pilliar R, Kandel RA, Grynpas MD, Filiaggi M, Valiquette N. (2000) The effect of pore size on the shear strength of attachment of in vitro-formed cartilage on porous Ti-6A1-4V substrates. World Biomaterials Conference, Hawaii, May

  • Agarwal, SC, Dumitriu M, Grynpas MD. (1999) Age-related changes in trabecular architecture in a medieval population. 5th Canadian Connective Tissue Conference, May 28-29, Montreal, Canada

  • Chachra D,Limeback H, Gross AE, Hutchinson CH, Zukor D, Schwartz M, Grynpas MD. (1999) Does fluoridated water alter the mechanical and material properties of human bone? IADR Annual Meeting, Vancouver, March

  • Chachra D, Limeback H, Gross AE, Hutchinson CH, Zukor D, Schwartz M, Grynpas MD. (1999) Does fluoridated water alter the mechanical and material properties of human bone? 5Th Canadian Connective Tissue Conference, May 28-29, Montreal, Canada

  • Ekstein S, Moran EL, James DF, Kasra M, Grynpas MD, Bogoch ER. (1999) The effect of arthritis on the mechanical properties of the cortex in long bones. 5Th Canadian Connective Tissue Conference, May 28-29, Montreal, Canada
  • Kasra M, Shirazi-Adl A, Grynpas MD. (1999) Dynamic characteristics of the rabbit knee joint. 5Th Canadian Connective Tissue Conference, May 28-29, Montreal, Canada
  • Mundy MA, Duong N, Grynpas MD, McKee MD, Goldberg HA, Hunter GK. (1999) The nucleation of hydroxyapatite by bone sialoprotein is modulated by osteopontin. 5Th Canadian Connective Tissue Conference, May 28-29, Montreal, Canada
  • Poitras MS, Goldberg HA, Grynpas MD, Hunter GK. (1999) Matrix-mediated mineralization of bone. IADR Annual Meeting, Vancouver, March

  • Poitras MS, Goldberg HA, Grynpas MD, Underhill TM, Hunter GK. (1999) Matrix mediated mineralization of bone. 5Th Canadian Connective Tissue Conference, May 28-29, Montreal, Canada

  • Sun Y-L, Hurtig M, Grynpas MD, Kandel RA. (1999) Mineralization induces changes in expression of specific genes in articular chondrocytes in vitro. 45th Annual Meeting, Orthop Res Soc, Anaheim, CA, February 1-4

  • Szweras M, Chedeville C, Sukhu B, Tenenbaum HC, Grynpas MD, Jahnen-Dechent W, and Dennis JW. (1999) The function of fetuin in osteogenesis. 5Th Canadian Connective Tissue Conference, May 28-29, Montreal, Canada
  • Waddell JE, Grynpas MD, Boynton EL. (1999) Histomorphometric analysis of the effect of polyethylene particles and surgery on bone formation. Annual Meeting of the Society for Biomaterial, Rhode Island, Providence, April 28- May 2
  • Woodfield T, Pilliar RM, Grynpas MD. (1999) Determination of subchondral bone - hyaline cartilage interfacial shear strength. Annual Meeting of the Society for Biomaterial, Rhode Island, Providence, April 28- May 2

  • Cerroni A, Grynpas MD. (1998) The effects of age, sex, and parity on bone mineral density of the spine in the rhesus macaques (Macaca mulatta) of Cayo Santiago. 4th Canadian Connective Tissue Conference, University of Western Ontario, London, Ontario June 5-6

  • Chachra D, Turner CH, Dunipace AJ, and Grynpas MD. (1998) Effect of fluoride administration on bone mineral in rabbits AADR, Minneapolis, March 4-7

  • Chachra D, Limeback H, Gross AE, Hutchinson C, Grynpas MD. (1998) Fluoride content, mechanical properties, and hardness of cancellous bone. 4th Canadian Connective Tissue Conference, University of Western Ontario, London, Ontario June 5-6

  • Chachra D, Limeback H, Gross AE, Hutchinson C, and Grynpas MD. (1998) Fluoride content, mechanical properties and hardness of human cancellous bone. IADR General Session & Exhibition, Nice, France, June 24-27

  • Grynpas M, Kasra M, Binkley N. (1998) Effect of 16-month zoledronaate treatment on bone mechanical prop-erties in the ovariectomized adult rhesus monkey. 4th Workshop Bisphosphonates, Mar 18-20, Davos, Switzerland

  • Grynpas MD, Kasra M, Binkley N, Meng C, Green J. (1998) Effect of 16-month zoledronate treatment on bone mechanical properties in the ovariectomized adult rhesus monkey. Second Joint Meeting of ASBMR and IBMS. San Francisco, CA, December 1-6

  • Hunter GK, Curtis HA, Grynpas MD, Simmer GP, Fincham A. (1998) Effects of recombinant amelogeninon hydroxyapatite formation. 6th International Conference on the Chemistry and Biology of Mineralized Tissues, Vittel, France, November 1-6

  • King L, Grynpas MD, Kandel R. (1998) Characterization of the mineral in calcified articular cartilagenous tissue formed in vitro. 4th Canadian Connective Tissue Conference, Univ of Western Ontario, London, Ontario June 5-6

  • Kuhn-Spearing L, Wu Y-T, Grynpas MD, Rey C, Gerstenfeld LC, Ackerman JL, Glimcher MJ. (1998) A study of the maturation of mineral deposits from osteoblast cell culture. 6th International Conference on the Chemistry and Biology of Mineralized Tissues, Vittel, France, November 1-6

  • Kuhn-Spearing L, Gerstenfeld LC, Landis WJ, Grynpas MD, Glimcher MJ. (1998) Dissociation of the biomineralization process from collagen deposition in specific osteosarcoma cell line cultures. 6th International Conference on the Chemistry and Biology of Mineralized Tissues, Vittel, France, November 1-6

  • Kuhn-Spearing L, Wu Y-T, Rey CC, Grynpas MD, Ackerman JL, Glimcher MJ. (1998) A comparison of the structural and chemical characteristics of the Ca-P mineral phase from bovine cortical and cancellous bone. 6th International Conference on the Chemistry and Biology of Mineralized Tissues, Vittel, France, November 1-6


  • Bushinsky DA, Singharetnam W, Grynpas MD, Asplin J, Coe FL. (1997) Effect of acidosis in urine supersaturation in genetic hypercalciuric stone forming rats. American Society of Nephrology 30th Annual Meeting, November 2-5

  • Cerroni AM, Grypas MD, Turnquist JE. (1997) Bone mineral density and osteoporosis in hte rhesus monkeys of Cayo Santiago. Amer J Phys Anthropol Annual Meeting Issue, April 3, St. Louis.

  • Chachra D, Lee JM, Grynpas MD. (1997) The effect of insulin-like growth factor-1 therapy on the mechanical properties of bone from ovariectomized rats. 43rd Annual Mtg. ORS Conference, San Francisco, February 9-13

  • Chachra D, Lee JM, Grynpas MD. (1997) The effect of insulin-like growth factor-1 therapy on ovariectomized rats. 25th European Symposium on Calcified Tissues. Harrogate International Centre, United Kingdom, Apr 25-29

  • Hajcsar EE, Robert EM, Moran EL, Grynpas MD, Bogoch ET. (1997) Osteonal parameters in experimental inflammatory arthritis and treatment with Zoledonate in rabbits. The Canadian Orthopaedic Association 52nd Annual Meeting, Hamilton, Canada, May 31-June 4.

  • Kandel R, Hurtig M, Grynpas MD. (1997) Comparison of the mineral in articular cartilagenous tissue formed in vitro to the mineral in calcified cartilage. First Smith & Nephew International Symposium. Advances in Tissue Engineering and Biomaterials, University of York, July 20-23

  • Kasra M, Grynpas MD (1997) Effect of cortical shell geometry on the vertebral body compressive failure load. 43rd Annual Mtg. ORS Conference, San Francisco, Feb 9-13

  • Kasra M, Parnianpour M, Wang J, Shirazi-Adl A, Grynpas M. (1997) Effect of strain rate on failure behaviour of the annulus fibrosus in tension. ASME, Nov 16-21, Dallas

  • Kuhn-Spearing L, Manot M, Gudinas A, Rey C, Grynpas MD, Glimcher M. (1997) The characterization and properties of anorganic nano-bone apatite. Bioceramics 10, Paris, October.

  • Peel SAF, Sun IL, Grynpas MD, Pilliar RM, Kandel RA. (1997) Cartilage formation on porous calcium polyphosphate (pCPP) in vitro. Canadian Connective Tissue Conference, Queen's University, Kingston, Ontario, Canada, May.

  • Podworny N, Kandel R, Renlund R, and M. Grynpas. (1997) The effect of the Zoledronate on cartilage and bone in the joint in a rabbit model of inflammatory arthritis. ASBMR 19th Annual Meeting, Cinncinati, Ohio, Sept 12


  • Bushinsky D, Bashir M, Riodon D, Nakagawa Y, Coe F, Grynpas M. (1996) Increasing dietary oxalate content does not alter stone composition in genetic hypercalciuric rats. 29th Annual Mtg of the Amer Soc of Nephrol, Nov 3-6, New Orleans, LO USA

  • Chachra D, Grynpas MD, and Lee JM. (1996) IGF-1 therapy in the mature ovariectomized rat. World Congress on Osteoporosis. Amsterdam.

  • Chachra D, Kasra M, Lee JM, and Grynpas MD. (1996) The mechanical properties of vertebrae: an evaluation of the ature ovariectomized rat model of postmenopausal osteoporosis. Fifth World Biomaterials Congress, Toronto, May 29-June 2.

  • Glimcher MJ, Kim H-M, Wu Y, Grynpas MD, Ackerman J, Morgan M, deRicqles A, Marino B, Kingston J. (1996) Further studies of the mineral phase of ~ 11.5 million year old giraffe bone. Third International Conference on Bone Diagenesis, Paris, March.

  • King LE, Grynpas MD, Tomlinson G, Vieth R. (1996) Pamidronate content and turnover in sternum vertebral body and iliac bones of dogs. Canadian Connective Tissue Conference, Toronto, June 21-23.

  • Lundon K, Grynpas M. (1996) A non-human primate model for study of the effects of polycystic ovarian disease on skeleton.7th Bone Morph Cong, Alghero, Italy, Oct 6-10.

  • Podworny N, Kandel R, Renlund R, and Grynpas MD. (1996) The effect of the bisphosphonate CGP 42'446 on the joint in a rabbit model of inflammatory arthritis. Third Workshop on Bisphosphonates, Davos, Switzerland, January 11-13.

  • Podworny N, Kandel R, Renlund R, Grynpas MD. (1996) The effect of the zoledronate (CGP 42'446) on the joint in a rabbit model of inflammatory arthritis. Canadian Connective Tissue Conference, Toronto, June 21-23.

  • Podworny N, Kandel R, Renlund R, Grynpas MD. (1996) The effect of the bisphosphonate zoledronate (CGP 42'446) on the joint in a rabbit model of inflammatory arthritis. ASBMR Conference, Seattle, WA, Sept.

  • Sodek KL, Tupy J, Sodek J, Grynpas MD. (1996) Relationship between bone mine-ralization and bone protein. Canadian Connective Tissue Conf, Toronto, June 21-23.

  • Turner C, Garetto L, Dunipace A, Zhang W, Wilson M, Grynpas MD, Chachra D, McClintock R, Peacock M (1996) Fluoride treatment increased serum IGF1 & bone mass, but not bone strength in rabbits. ASBMR Conference, Seattle, WA, September

  • Wells JD, Grynpas MD, and Pilliar RM. (1996) A novel porous bone substitute. Fifth World Biomaterials Congress, Toronto, May 29-June 2.

  • Zérath E, Novikov V, Grynpas MD, Bakulin A, Holy X, LeBlanc A, and Oganov V. (1996) Consequences of a 11.5-day spaceflight on bone mineralization in the rhesus monkey. Calcified Tissue Conference, Jerusalem, Israel, March 26.


  • Chachra D, Kasra M, Lee JM, and Grynpas MD. (1995) An evaluation of the mature ovariectomized rat model of postmenopausal osteoporosis: the mechanical properties of vertebrae. Canadian Biomaterial Society Meeting, Ottawa, May 17.

  • Grynpas MD, Renlund R, and Pritzker KPH. (1995) The effect of pamidronate in a new model of immobilization in the dog. XIIth International Conference on Calcium Regulating Hormones, Melbourne, Australia, February 14-19.

  • Grynpas MD, Lundon K, Kasra M. (1995) The effect of androgen treatments on the quality and quantity of cortical bone in the young female monkey. Satellite Workshop of the XIIth ICCRH Conference, Hyatt Coolum Resort, Queensland, Australia, February 19-23

  • Grynpas MD, Boyce TM, Schaffler MG. (1995) A possible relation between changes in bone mineralization with age and bone fragility. The Fifth International Conference on the Chemistry and Biology of Mineralized Tissues.

  • Kasra M, Catelas I, Tomlinson G, and Grynpas MD. (1995) Torsional behaviour of trabecular bone: effects of bone marrow, density and strain rate. 41st Annual Meeting, Orthopaedic Research Society, Orlando, Florida, February 13-16

  • Vanin C, Grynpas MD, Casper RF. (1995) The effect of estrogen and androgen on bone density in the aged ovariectomized rat. Regional Symposium on Skeletal Biology and Metabolic Disease. University of Western Ontario, London, Ontario, April 1.

  • Vanin C, Lammers M, MacLusky N, Casper R, and Grynpas MD. (1995) Androgens and bone density in the aged ovariectomized rat. American Society for Bone and Mineral Research Meeting, Baltimore, MD, September 11.


  • Chachra D, Kasra M, Vanin C, MacLuskey N, Casper R, Grynpas MD. The effect of different hormone replacement therapy treatment regimens on the mechanical properties of rat vertebrae. 2nd World Congress on Biomechanics, Amsterdam, July, 1994.

  • Guo W, Kim S, Grynpas MD, Pritzker KPH, Pilliar RM. Calcium polyphosphate fibres for composite biomaterials - Degradation studies. The 20th Annual Meeting of the Society for Biomaterials, April 5-9, 1994, Boston, USA.

  • Grynpas MD, Renlund R, and Pritzker KPH. (1994) The localization of pamidronate (APD) in bone. Second Workshop on Bisphosphonates, Davos, Switzerland, April 14-17
  • Grynpas MD, Holmyard D, Nespeca R, Pritzker KP. Bone mineralization and histomorphometry in biopsies of patients treated with fluoride. Scanning Microscopy 1994 Meeting, Toronto, May 7-12, 1994.
  • Kasra M, Pilliar R, Grynpas MD. Effect of surface of a newly implanted material on strain pattern within the bone-implant interface. 2nd World Congress on Biomechanics, Amsterdam, July, 1994.
  • Kasra M, Grynpas MD. The effect of geometry at a microstructural level on the mechanical behaviour of trabecular bone structure. 2nd World Congress on Biomechanics, Amsterdam, July, 1994.
  • Kasra M, and Grynpas MD. (1994) Finite element dynamic response analysis of trabecular bone: Effect of bone marrow. ASME, Chicago, November 6-11.
  • Koo I, Grynpas MD, Holmyard D, Tenenbaum HC. Backscattered electron image assessment of mineral density in osteogenic cultures. 13th International Conference on Oral Biology, IADR, March 14-16, 1994.
  • Koo I, Torontali M, Holmyard D, Grynpas MD, Tenenbaum HC. Assessment of mineral density in bone formed in vitro. Scanning Microscopy Meeting, Toronto, May 7-12, 1994.
  • Vanin CM, MacLusky NJ, Chachra D, Kasra M, Grynpas MD, and Casper RF. Bone mineral density and biomechanics in aged ovariectomized rats treated with estrogen and norethindrone or norgestimate. Canadian Fertility and Andrology Society, 1994

  • Bushinsky DA, Lam BC*, Nespeca R.*, Sessler NE*, Grynpas MD. Decreased bone carbonate content in response to metabolic, but not respiratory, acidosis. 15th Annual meeting ASBMR, Tampa, Florida, Sept. 18-22, 1993.

  • Grynpas MD, Kasra M, Dumitriu M, Nespeca R, Very JM and Mertz BP. (1993) Recovery from pamidronate (APD): A two year study in the dog. 4th International Symposium on Osteoporosis and Consensus Development Conference, Hong Kong, March 27-April 2, 1993.
  • Grynpas MD, Acito A, Kasra M. (1993) The effect of pamidronate (APD) on the mechanical properties of canine bone. ECCO7, Jerusalem, November 14-18, 1993.
  • Lundon K, Grynpas MD. (1993) The longterm effects of mild androgenic stimulus on trabecular bone in the young female Cynomolgus monkey: A model for polycystic ovarian disease. 4th International Symposium on Osteoporosis and Consensus Development Conference, Hong Kong, March 27-April 2, 1993.
  • Sukyoung K, Tetsuya S, Pilliar RM, Grynpas MD, Pritzker KPH. (1993) Enzymatic degradation of calcium metaphosphate glasses - The effects of Ca/P ratios. 14th Annual Conference of the Canadian Biomaterial Society, McMaster University, Hamilton, Ontario, June 2-4, 1993.
  • Vanin CM, MacLusky NJ, Grynpas MD, Casper RF. (1993) The effect of a new HRT with interrupted progestin on bone denstiy in the aged oophorectomized rat. NAMS (North American Menopause Society), San Diego, California.

  • Babayan AM, Pilliar Rm, Grynpas MD. (1992) Resorbable short-fibre reinforced composites for fracture fixation. 4th World Biomaterials Congress, Berlin, Apr 24-28.
  • Gahunia HK, Lemaire C, Grynpas MD, Cross A, Kessler MJ, Pritzker KPH. (1992) Assessment of cartilage degeneration by analytical magnetic resonance imaging. Society of Magnetic Resonance in Medicine, 11th Annual Scientific Mtg, Berlin, Aug 8-14
  • Grynpas MD, Acito A, Kasra M, Renlund R, Pritzker KPH. (1992) The effect of pamidronate (APD) administration on canine bone. XIth ICCRH Conference, Florence, Italy April 24-29.
  • Grynpas MD, Lieberman IH, Bogoch ER, Pritzker KPH. (1992) The effect of rheumatoid arthritis on subchondral bone - The Canadian Orthopaedic Research Society, 26th Meeting, Toronto, June 20-21, 1992
  • Grynpas MD, Holmyard D and Pritzker KPH. (1992) Bone mineral quality in biopsies of fluoride treated osteoporotic patients. 6th International Congress on Bone Morphometry, Lexington, Kentuky, October 4-9, 1992
  • Kasra M, Grynpas MD. (1992) A finite element study of trabecular bone: Effect of bone marrow. 39th Annual Meeting, ORS, San Francisco, California, February 15-18, 1993
  • Kasra M, Grynpas MD. (1992) The efect of testosterone on the mechanical properties of primate cortical bone. 39th Annual Meeting, ORS, San Francisco, February 15-18, 1993
  • Kasra M, Grynpas MD. (1992) The effect of ovariectomy on the mechanical properties of primate cortical bone. 38th Annual Meeting, Orthopaedic Research Society, Feb 17-20.
  • Kim S, Shinozaki T, Pilliar RM, Grynpas MD, Pritzker KPH (1992) Calcium phosphates fibers for biodegradable implants. Canadian Biomaterial Society meeting, Kingston, Ontario, August, 1992
  • Lundon K, Grynpas MD. (1992) The long term effect of ovariectomy on trabecular bone in the young adult Cynomolgus monkey. 39th Annual Meeting, ORS, San Francisco, Feb 15-18, 1993
  • Lundon K, Grynpas MD. (1992) Long-term changes in the quality and quantity of both trabecular and cortical bone in the young ovariectomized Cynomolgus monkey: A Comparison Of Histomorphometric And Density Fractionation Techniques. 6th International Congress on Bone Morphometry, Lexington, Kentuky, October 4-9, 1992
  • Vanin CM, Maclusky NJ, Grynpas MD, Casper RF. (1992) Effect of estrogen and progestin regimens on bone density in the aged ovariectomized rat - Second Symposium/Workshop on the Rat Skeleton, Chicago, May 11-14, 1992
  • Vanin CM, MacLusky NJ, Grynpas MD, Casper R. (1992) Effect of estrogen and progestin regimens on bone density in the aged ovariectomized rat. North America Menopause Society Meeting. Cleveland, Ohio USA, September 17-20, 1992

  • Acito A, Grynpas MD, Lee JM. (1991) The effect of APD treatment on the stiffness and mineralization of canine cortical bone. Can Biomaterial Society Meeting, Halifax, June.
  • Cerroni A, Grynpas MD, Pritzker KPH, Turnquist JE, Kessler MJ, Melbye FJ. (1991) Spontaneous malformations of the vertebral column in Patas monkeys. Canadian Association for Physical Anthropology, 19th Annual Meeting, October.
  • Cheng P-T, Bader SM, Grynpas MD. (1991) Biophasic effects of fluoride on canine femoral cortical and cancellous bones. Combined Meeting of the Orthopaedic Research Societies of USA, JAPAN and CANADA, October 21-23, Banff Alberta
  • Gahunia HK, Lemaire C, Cross A, Grynpas MD, Pritzker KPH. (1991) Magnetic resonance imaging of the knee joint of Rhesus monkey: Assessment of cartilage quality in osteoarthritis. Society of Magnetic Resonance in Medicine. August 16.
  • Grynpas MD, Holmyard D, Pritzker KPH. (1991) Bone mineral quality in biopsies of osteoporotic patients treated with fuoride. XXII European Symposium on Calcified Tissues, Vienna, March 10- 4
  • Grynpas MD, Renlund R, Pritzker KPH. (1991) The effect of short term pamidronate (APD) administration on canine bone mineral and matrix. American Society for Bone and Mineral Research San Diego CA, August 24-28.
  • Landis WJ, Grynpas MD, Gerstenfeld LC. (1991) Utilization of strontium as a marker for calcium in mineralizing osteoblast cell cultures. Combined Meeting of the Orthopaedic Research Societies of USA, JAPAN and CANADA, October 21-23, Banff Alberta

  • Grynpas MD, Lieberman IH*, Bogoch E, Pritzker KPH. (1990) Subchondral bone in rheumatoid arthritis. Second Bath Conference on Osteoporosis and Bone Mineral Measurement, June 25-27, Bath, England
  • Grynpas MD, Prizker KPH, Very JM, Mertz. (1990) Changes in mineralization profiles due to long term administration of APD in the dog. Third Internationa Symposium on Osteoporosis. Copenhagen, Denmark, October 14-20

  • Châteaubert JMD*, Grynpas MD, Kessler MJ, Pritzker KPH. (1989) Morphometric studies of the articular cartilage of Rhesus macaques with spontaneous osteoarthritis. 23rd Annual Meeting of the Canadian Orthopaedic Research Society, Toronto, Canada, May.
  • Grynpas MD, Alpert B*, Lieberman IH*, Pritzker KPH. (1989) Changes in bone mineralization in osteoarthritis. The XXI European Symposium on Calcified Tissues, Jerusalem Israel, March.
  • Grynpas MD, Tran T*, Holmyard D, Simmons DJ. (1989) Mineralization changes in microgravity. ASBMR/ICCRH - 1989 MEETING, Montreal Quebec Canada, September.
  • Lucas S*, Bogoch E, Grynpas MD. (1989) Experimental arthritis in a rabbit model. 23rd Annual Meeting of the Canadian Orthopaedic Research Society, Toronto, Canada, May.

  • Grynpas MD, Marie P. (1988) Low doses of stable strontium alter the quality and quantity of bone in rats. The American Society for Bone and Mineral Res, New Orleans, June.
  • Grynpas MD, Tenenbaum HC, Holmyard DP. (1988) The emergence and maturation of the first apatite crystals in an in vitro bone formation system. 3rd International Conference on the Chemistry and Biology of Mineralized tissue, Chatham Massachussetts, October.
  • Grynpas MD, Pastoureau P, Chavassieux P, Boivin G. (1988) Effect of therapeutic doses of sodium fluoride on the quality and quantity of ovine bones. International Workshop on Fluoride and Bone, Niagara-on-the-Lake Ontario Canada, October.
  • Hunter GK, Grynpas MD. (1989) Differential metabolism of glycosaminoglycans in rat bone. Conn Tiss Res 22(1-4):866.
  • Liberman I*, Bogach E, Pritzker KPH, Grynpas MD. (1988) Subchondral bone changes in the femoral heads of patients with rheumatoid arthritis. 22nd Canadian Orthopaedic Res. Society, Ottawa, Ontario, June.
  • Pritzker KPH, Grynpas MD, Brown RD. Bone quality and bone kinetics in cyclic osteoporosis. Conn Tiss Res 22(1-4):910, 1989.
  • Pritzker KPH, Grynpas MD, Harrison JE. (1988) Observed versus predicted concentrations of bone fluoride in osteoporotic patients: Implications for assessment of fluoride effect. International Workshop on Fluoride and Bone, Niagara-on-the-Lake Ontario Canada, October.

  • Grynpas MD, Cheng P-T. (1987) The effect of fluoride on bone mineral. 8th Annual Conference of the Canadian Biomaterial Society, Toronto, May p. 40.
  • Hancock RGV, Grynpas MD, Pritzker KPH. (1987) Bones lie. 52nd Annual meeting of the Society for American Archeology, Toronto, May.
  • Huckell CB*, Grynpas MD, Pritzker KPH. (1987) Ageing and osteoporosis in free ranging Rhesus monkeys. 21st Annual Meeting of the Canadian Orthopaedic Research Society, London, Ontario, June 29.

  • Grynpas MD, Fuller M, Cheng P-T. (1986) The effect of fluoride on demineralization of cortical bone. Transaction of the 32nd Meeting of the ORS, New Orleans, February.
  • Katz I*, Pritzker KPH, Grynpas MD. (1986) Qualitative bone mineral changes in osteoporosis. J Bone Miner Res 1(Suppl.), June 26.
  • Pritzker KPH, Châteauvert J*, Grynpas MD. (1986) Calcium phosphorus magnesium and sulfur content of osteoarthritic cartilage. Royal College of Physicians and Surgeons of Canada Meeting, Toronto, September.

  • Alpert B*, Grynpas MD, Pritzker KPH. (1985) Qualitative changes in subchondral bone mineral in osteoarthritis. Transactions of the 31st meeting of the Orthopaedic Research Society, Las Vegas, January p. 77.
  • Alpert B*, Grynpas MD, Pritzker KPH. (1985) Properties of subchondral bone mineral in osteoarthritis. Canadian Orthopaedic Research Society Meeting, Hamilton, Ontario, June.
  • Grynpas MD, Pritzker KPH, Kessler MJ. (1985) Cortical bone aging in fee ranging Rhesus monkeys. Seventh Annual Meeting of the American Society of Primatologists, Niagara Falls, June.
  • Simmons, ED*, Grynpas MD, Pritzker KP. (1985) Bone mineral changes in aging human cortical bone. Transaction of the 31st meeting of the ORS, Las Vegas, January p. 11.
  • Simmons ED*, Grynpas MD, Pritzker KPH. (1985) Mineralization Profile:   A sensitive indicator of bone mineral pathology. Canadian congress of Laboratory Medicine, Edmonton, Alberta, June.

  • Evequoz V, Zavadil-Grob C, Grynpas M, Schnyder J, Trechsel U, Fleisch H, Dayer J-M. (1984) Effects of crystals in cell-cell interactions controlling collagenase, PGE2 and plasminogen activator production. Calcif Tissue Int 36:458.
  • Grynpas MD, Hunter GK, Simmons ED*. (1984) The relationship between proteoglycan and bone mineral in newborn and adult rabbits. Calcif Tissue Int 36:486.
  • Reid AD, Grynpas MD, Pritzker KPH, Harrison JE. (1984) Structural changes induced by fluoride in rat bones. Proceedingsof the electron microscopic society of America 1984.   Edited by G.W. Bailey, San Francisco Press, p. 718-719

  • Bonar LC, Grynpas MD, Glimcher MJ. (1983) Use Of Bone Density Fractionation To Study Mineral Changes In Bone Disorders. Trans. Orthopaedic Research Society 8:271.
  • Grynpas MD, Bonar LC, Glimcher MJ. (1983) The Failure To Detect Amorphous Calcium Phosphate (Acp) In Bone Mineral And The Acp Theory Of Bone Mineral. Calcif Tissue Int 35:supplement.
  • Grynpas MD. (1983) Changes In Bone Mineral Structure In Immobilized Monkeys. Calcified Tissue Int 35:662.

  • Grynpas MD, Bonard LC, Glimcher MJ, Morrison TI. (1982) Calcium EXAFS Studies Of Mineralized Tissues And Synthetic Calcium Phospates. Trans. Orthopaedic Research Society 7:287.

  • Boivin G, Lian JB, Grynpas MD, Glimcher MJ. (1981) The appearance of   carboxyglutamic acid in subcutaneous calcinosis. Calcif Tissue Int 33:314.
  • Bonar LC, Roufosse AH, Grynpas MD, Glimcher MJ. (1981) X-ray diffraction crystallinity studies of developing, maturing and aging bone. Calcif Tissue Int 31:68
  • Grynpas MD, Bonar LC, Glimcher MJ. (1981) Changes in bone mineral with age. Trans Orthopaedic Research Society 6:61.
  • Grynpas MD. (1981) Probing the atomic environment of calcium and phosphorus in bone tissues by Exafs, and new methods in spectroscopy. Journal of Rheumatology 8:1019.

  • Grynpas MD, Eyre DR, Kirschner Da. (1980) Collagen of the intervertebral disc:  X-ray diffraction packing of types I and II collagen. Trans Orthopaedic Research Society 5:13.
  • Grynpas MD, Bonar LC, Glimcher MJ. (1980) Recent studies on the structure of bone mineral. Calcif Tissue Int 31:69.
  • Grynpas MD, Bonar LC. (1980) EXAFS studies of the mineralized phase of bone and other mineralized tissue. SSRL Report (302), May.

  • Bonar LC, Roufosse AH, Sabine W, Grynpas MD, Glimcher MJ. (1979) X-Ray diffraction studies of the extent of crystallinity of the mineral component of density separated bone fractions and newly synthesized bone. Calcified Tissue International 28:17A.

 

 

Book Chapters and Proceedings

  • Grynpas MD. (2001) The concept of bone quality in osteoporosis. In: Ageing, osteoporosis and dental implants ,edited by T. Albrektsson, U. Lekholm, H. Tenenbaum, G. Zarb. Quintessence International, Berlin. (in press)
  • Grynpas MD, Chachra D, Limeback H (2000) The action of fluoride on bone. In: The Osteoporosis Primer. Cambridge University Press (in press)

  • Filiaggi MJ, Wells JD, Peel SAF, Pilliar RM, Grynpas MD, Kandel RA. (1998) Condensed calcium phosphate for soft tissue and bone repair/regeneration. In: Bioceramics Volume 11, (eds) LeGeros RZ, LeGeros JP. World Scientific Publishing Co. Pte. Ltd., New York, (Nov) pp. 341-344.

  • Kasra M, Parnianpour M, Wang JL, Shirazi-Adi A, and Grynpas MD. (1998) Mechanical behaviour of annulus fibrosus under tensile dynamic loading: Effect of loading rate. In: Integrated Design and Process Technology. eds. A.E. Egin and A. Ertas Society for Design and Process Science, USA, Vol. 1, pp. 49-54.

  • Grynpas MD, Kasra M, Acito A. (1996) The mechanical properties of canine bone after Pamidronate treatment. In: Bisphosphonates - Improved treatment of osteolysis in malignant and non-malignant indications. eds. K. Possinger and R. Ziegler, Ciba-Geigy Verlag, Wehr, pp.93-106.
  • Hancock RGV, Grynpas MD, Akesson K, Oberant K, Turnquist J, Kessler MJ. (1993) Baselines and variabilities of major and trace elements in bone. In: Molecular archaeology of prehistoric human bone. Proceedings of the Third Advanced Seminar on Paleodiet. ed. J.B. Lambert and G. Grupe, Springer Verlag, Berlin, pp. 192-201.
  • Simmons DJ, Grynpas MD. (1990) Mechanisms of deposition of bone in vivo. In: Bone, Volume 1, B.K. Hall ed., The Telford Press, New-Jersey, pp. 193-302.
  • Pollard A, Pritzker KPH, Grynpas M. (1986) Disorders of calcium, magnesium, and bone metabolism. Chapter 17. In:  Applied Chemistry of Clinical Disorders.  Edited by Dr. Gornall. J.B. Lippincott, pp. 403-419.
  • Robertson WG, Bach DW, Finlayson B, Francis MD, Garside J, Grynpas MD, Hesse A, Klee WE, McCarty DJ, Moreno EC, Smith LK, Vahlensiek EW. (1982) Mechanisms of pathological calcification. In:  Biological mineralization and demineralization, edited by G.H.  Nancollas. Springer-Verlag, Berlin pp. 367-389.